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ISSN - 20790597, EISSN - 20790600, Russian Journal of Genetics: Applied Research, 2011, vol. 1, p. 290-301

Prospects for designing new generation anti-tuberculosis vaccines

Tat'kov S. I., Deineko E. V., Furman D. P.

Recent progress in designing new vaccines against tuberculosis is concisely reviewed. Data on administration of various secreted Mycobacterium tuberculosis antigens as components of subunit vaccines are briefed. The need in constructing artificial antigens comprising several M. tuberculosis antigens (epitopes) is illustrated by particular examples. The prospect of developing an "edible" vaccine against tuberculosis involving transgenic plants is discussed. © 2011 Pleiades Publishing, Ltd.