Sodbo Zh Sharapov, Alexandra S Shadrina, Yakov A Tsepilov, Elizaveta E Elgaeva, Evgeny S Tiys, Sofya G Feoktistova, Olga O Zaytseva, Frano Vuckovic, Rafael Cuadrat, Susanne Jäger, Clemens Wittenbecher, Lennart C Karssen, Maria Timofeeva, Therese Tillin, Irena Trbojević-Akmačić, Tamara Štambuk, Najda Rudman, Jasminka Krištić, Jelena Šimunović, Ana Momčilović, Marija Vilaj, Julija Jurić, Anita Slana, Ivan Gudelj, Thomas Klarić, Livia Puljak, Andrea Skelin, Antonia Jeličić Kadić, Jan Van Zundert, Nishi Chaturvedi, Harry Campbell, Malcolm Dunlop, Susan M Farrington, Margaret Doherty, Concetta Dagostino, Christian Gieger, Massimo Allegri, Frances Williams, Matthias B Schulze, Gordan Lauc, Yurii S Aulchenko. Replication of 15 loci involved in human plasma protein N-glycosylation in 4802 samples from four cohorts. Glycobiology. 2020 June 10. doi: 10.1093/glycob/cwaa053
Mikhail Churnosov, Irina Ponomarenko, Evgeny Reshetnikov, Alexey Polonikov, Irina Verzilina, Inna Sorokina, Elizaveta E Elgaeva, Yakov A Tsepilov,Anna Yermachenko, Volodymyr Dvornyk, Mikhail Churnosov. Candidate genes for age at menarche are associated with endometriosis. Reproductive BioMedicine Online. 2020 May 14. doi: 10.1016/j.rbmo.2020.04.016
Yakov A. Tsepilov, Maxim B. Freidin, Alexandra S. Shadrina, Sodbo Z. Sharapov, Elizaveta E. Elgaeva, Jan van Zundert, Lennart С. Karssen, Pradeep Suri, Frances M. K. Williams, Yurii S. Aulchenko. Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions. Commun Biol. 2020; 3: 329. Published online 2020 Jun 25. doi: 10.1038/s42003-020-1051-9
2019:
Zenin A, Tsepilov Y, Sharapov S, Getmantsev E, Menshikov LI, Fedichev PO, Aulchenko Y. Identification of 12 genetic loci associated with human healthspan. Commun Biol. 2019 Jan 30;2:41. doi: 10.1038/s42003-019-0290-0.
Freidin MB, Tsepilov YA, Palmer M, Karssen LC, Suri P, Aulchenko YS, Williams FMK; CHARGE Musculoskeletal Working Group. Insight into the genetic architecture of back pain and its risk factors from a study of 509,000 individuals. Pain. 2019 Feb 6. doi: 10.1097/j.pain.0000000000001514.
Sharapov SZ, Tsepilov YA, Klaric L, Mangino M, Thareja G, Shadrina AS, Simurina M, Dagostino C, Dmitrieva J, Vilaj M, Vuckovic F, Pavic T, Stambuk J, Trbojevic-Akmacic I, Kristic J, Simunovic J, Momcilovic A, Campbell H, Doherty M, Dunlop MG, Farrington SM, Pucic-Bakovic M, Gieger C, Allegri M, Louis E, Georges M, Suhre K, Spector T, Williams FMK, Lauc G, Aulchenko YS. Defining the genetic control of human blood plasma N-glycome using genome-wide association study. Hum Mol Genet. 2019 Jun 15;28(12):2062-2077. doi: 10.1093/hmg/ddz054.
Shadrina AS, Sharapov SZ, Shashkova TI, Tsepilov YA. Varicose veins of lower extremities: Insights from the first large-scale genetic study. PLoS Genet. 2019 Apr 18;15(4):e1008110. doi: 10.1371/journal.pgen.1008110.
Alexander S. Zlobin, Natalia A. Volkova, Pavel M. Borodin, Tatiana I. Aksenovich, Yakov A. Tsepilov. Recent advances in understanding genetic variants associated with growth, carcass and meat productivity traits in sheep (Ovis aries): an update.Archives Animal Breeding.doi: 10.5194/aab-62-579-2019
Elgaeva EE, Tsepilov Y, Freidin MB, Williams FMK, Aulchenko Y, Suri P. ISSLS Prize in Clinical Science 2020. Examining causal effects of body mass index on back pain: a Mendelian randomization study. Eur Spine J. 2019 Dec 3. doi: 10.1007/s00586-019-06224-6. [Epub ahead of print] PubMed PMID: 31797139.
Oscorbin IP, Shadrina AS, Kozlov VV, Voitsitsky VE, Filipenko ML. Absence of EGFR C797S Mutation in Tyrosine Kinase Inhibitor-Naïve Non–Small Cell Lung Cancer Tissues. Pathol Oncol Res. 2019 Jun 26. doi: 10.1007/s12253-019-00683-4. [Epub ahead of print]
2018:
M.S. Taylor, I. Altukhov, K.R. Molloy, P. Mita, H. Jiang, E.M. Adney, A. Wudzinska, S. Badri, D. Ischenko, G. Eng, K.H. Burns, D. Fenyö, B.T. Chait, D. Alexeev, M.P. Rout, J.D. Boeke, and J. LaCava, Dissection of affinity captured LINE-1 macromolecular complexes, eLife 2018.7:e30094 DOI: 10.7554/eLife.30094
Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Amininejad L, Bouma G, Hoentjen F, Löwenberg M, Oldenburg B, Pierik MJ, Vander Meulen-de Jong AE, Janneke van der Woude C,Visschedijk MC; International IBD Genetics Consortium, Lathrop M, Hugot JP, Weersma RK, De Vos M, Franchimont D, Vermeire S, Kubo M, Louis E, Georges M. IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes. Nat Commun. 2018 Jun 21;9(1):2427. doi:
10.1038/s41467-018-04365-8
Klimenko NS, Tyakht AV, Popenko AS, Vasiliev AS, Altukhov IA, Ischenko DS, Shashkova TI, Efimova DA, Nikogosov DA, Osipenko DA, Musienko SV, Selezneva KS, Baranova A, Kurilshikov AM, Toshchakov SM, Korzhenkov AA, Samarov NI, Shevchenko MA, Tepliuk AV, Alexeev DG. Microbiome Responses to an Uncontrolled Short-Term Diet Intervention in the Frame of the Citizen Science Project. Nutrients. 2018
May 8;10(5). pii: E576. doi: 10.3390/nu10050576
Shadrina A & Tsepilov Y, Sokolova E, Smetanina M, Voronina E, Pakhomov E, et al. Genome-wide association study in ethnic Russians suggests an association of the MHC class III genomic region with the risk of primary varicose veins. Gene. 2018;659: 93–99. doi:10.1016/j.gene.2018.03.039
Fazullina ON, Klimontov VV, Konenkov VI, Shevchenko AV, Prokofiev VF, Tsepilov YA. Associations of polymorphisms in the gene promoters of cytokines and matrix metalloproteinases with bone mineral density in postmenopausal type 2 diabetic women. Diabetes Mellit. 2018;21. doi:10.14341/DM8825
Boyarskikh UA, Shadrina AS, Smetanina MA, Tsepilov YA, Oscorbin IP, Kozlov V V., et al. Mycoplasma hyorhinis reduces sensitivity of human lung carcinoma cells to Nutlin-3 and promotes their malignant phenotype. J Cancer Res Clin Oncol. 2018;0. doi:10.1007/s00432-018-2658-9
Shadrina A & Tsepilov Y, Smetanina M, Voronina E, Seliverstov E, Ilyukhin E, et al. Polymorphisms of genes involved in inflammation and blood vessel development influence the risk of varicose veins. Clin Genet. 2018; doi:10.1111/cge.13362
Shadrina A, Voronina E, Smetanina M, Tsepilov Y, Sevost’ianova K, Shevela A, et al. Polymorphisms in inflammation-related genes and the risk of primary varicose veins in ethnic Russians. Immunol Res. 2018;66: 141–150. doi:10.1007/s12026-017-8981-4
Suri P, Palmer MR, Tsepilov YA, Freidin MB, Boer CG, Yau MS, et al. Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain. PLOS Genet. 2018;14. doi:10.1371/journal.pgen.1007601
Y A Tsepilov, S Z Sharapov, O O Zaytseva, J Krumsek, C Prehn, J Adamski, G Kastenmüller, R Wang-Sattler, K Strauch, C Gieger, Y S Aulchenko; A network-based conditional genetic association analysis of the human metabolome, GigaScience, Volume 7, Issue 12, 1 December 2018, giy137, https://doi.org/10.1093/gigascience/giy137
T. S. Frolova, S. Z. Sharapov, O. I. Sinitsyna, T. G. Tolstikova, I. A. Grigoriev, S. V. Morozov, Y. V. Yushkova. New Ionic Conjugates Based on α-Tocopheryl Succinate as Potential Cytotoxic Agents. Russian Journal of Bioorganic Chemistry, May 2018, Volume 44, Issue 3, pp 330–336. doi: 10.1134/S1068162018030068
2017:
Shen X, Klarić L, Sharapov S, Mangino M, Ning Z, Wu D, Trbojević-Akmačić I, Pučić-Baković M, Rudan I, Polašek O, Hayward C, Spector TD, Wilson JF, Lauc G, Aulchenko YS. Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation. Nat Commun. 2017 Sep 6;8(1):447. doi: 10.1038/s41467-017-00453-3. PubMed PMID: 28878392; PubMed Central PMCID: PMC5587582.
А. C. Злобин, С. Ж. Шарапов, В. П. Гурьев, М. P. Бевова, Я. А. Цепилов, Т. М. Сивцева, У. А. Боярских, Е. А. Соколова, Ю. С. Аульченко, М. Л. Филипенко, В. Л. Осаковский. Популяционно-генетический анализ экзомов представителей якутского этноса. ДОКЛАДЫ АКАДЕМИИ НАУК, 2017, том 474, No 4, с. 505–509
Alexandra Shadrina, Elena Voronina, Mariya Smetanina, Yakov Tsepilov, Kseniya Sevost’ianova, Andrey Shevela, Evgenii Seliverstov, Elena Zakharova, Evgeny Ilyukhin, Alexander Kirienko, Igor Zolotukhin, Maxim Filipenko. Immunologic Research. Polymorphisms in inflammation-related genes and the risk of primary varicose veins in ethnic Russians.
Frolova, T.S., Lipeeva, A.V., Baev, D.S., Y.A. Tsepilov et al. Apoptosis as the basic mechanism of cytotoxic action of ursolic and pomolic acids in glioma cells Mol Biol (2017) 51: 705
2016 г.
Torgasheva AA, Borodin PM. Cytological basis of sterility in male and female hybrids between sibling species of grey voles Microtus arvalis and M. levis. Sci Rep. 2016 Nov 4;6:36564. doi: 10.1038/srep36564. PubMed PMID: 27811955.
Schirmer M, Smeekens SP, Vlamakis H, Jaeger M, Oosting M, Franzosa EA, Jansen T, Jacobs L, Bonder MJ, Kurilshikov A, Fu J, Joosten LA, Zhernakova A, Huttenhower C, Wijmenga C, Netea MG, Xavier RJ. Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity. Cell. 2016 Nov 3;167(4):1125-1136.e8. doi: 10.1016/j.cell.2016.10.020. PubMed PMID: 27814509.
Bonder MJ, Kurilshikov A, Tigchelaar EF, Mujagic Z, Imhann F, Vila AV, Deelen P, Vatanen T, Schirmer M, Smeekens SP, Zhernakova DV, Jankipersadsing SA, Jaeger M, Oosting M, Cenit MC, Masclee AA, Swertz MA, Li Y, Kumar V, Joosten L, Harmsen H, Weersma RK, Franke L, Hofker MH, Xavier RJ, Jonkers D, Netea MG, Wijmenga C, Fu J, Zhernakova A. The effect of host genetics on the gut microbiome. Nat Genet. 2016 Nov;48(11):1407-1412. doi: 10.1038/ng.3663. PubMed PMID: 27694959.
Karssen LC, van Duijn CM, Aulchenko YS. The GenABEL Project for statistical genomics. F1000Res. 2016 May 19;5:914. doi: 10.12688/f1000research.8733.1. eCollection 2016. PubMed PMID: 27347381; PubMed Central PMCID: PMC4916982.
Zhernakova A, Kurilshikov A, Bonder MJ, Tigchelaar EF, Schirmer M, Vatanen T, Mujagic Z, Vila AV, Falony G, Vieira-Silva S, Wang J, Imhann F, Brandsma E, Jankipersadsing SA, Joossens M, Cenit MC, Deelen P, Swertz MA; LifeLines cohort study, Weersma RK, Feskens EJ, Netea MG, Gevers D, Jonkers D, Franke L, Aulchenko YS, Huttenhower C, Raes J, Hofker MH, Xavier RJ, Wijmenga C, Fu J. Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity. Science. 2016 Apr 29;352(6285):565-9. doi:10.1126/science.aad3369. Epub 2016 Apr 28. PubMed PMID: 27126040.
Falony G, Joossens M, Vieira-Silva S, Wang J, Darzi Y, Faust K, Kurilshikov A, Bonder MJ, Valles-Colomer M, Vandeputte D, Tito RY, Chaffron S, Rymenans L, Verspecht C, De Sutter L, Lima-Mendez G, D'hoe K, Jonckheere K, Homola D, Garcia R, Tigchelaar EF, Eeckhaudt L, Fu J, Henckaerts L, Zhernakova A, Wijmenga C, Raes J. Population-level analysis of gut microbiome variation. Science. 2016 Apr 29;352(6285):560-4. doi: 10.1126/science.aad3503. Epub 2016 Apr 28. PubMed PMID: 27126039.
Fieten H, Gill Y, Martin AJ, Concilli M, Dirksen K, van Steenbeek FG, Spee B, van den Ingh TS, Martens EC, Festa P, Chesi G, van de Sluis B, Houwen RH, Watson AL, Aulchenko YS, Hodgkinson VL, Zhu S, Petris MJ, Polishchuk RS, Leegwater PA, Rothuizen J. The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: a new canine model for copper-metabolism disorders. Dis Model Mech. 2016 Jan;9(1):25-38. doi: 10.1242/dmm.020263. PubMed PMID: 26747866; PubMed Central PMCID: PMC4728329. [IF=4.97]
Wang Y, Klarić L, Yu X, Thaqi K, Dong J, Novokmet M, Wilson J, Polasek O, Liu Y, Krištić J, Ge S, Pučić-Baković M, Wu L, Zhou Y, Ugrina I, Song M, Zhang J, Guo X, Zeng Q, Rudan I, Campbell H, Aulchenko Y, Lauc G, Wang W. The Association Between Glycosylation of Immunoglobulin G and Hypertension: A Multiple Ethnic Cross-Sectional Study. Medicine (Baltimore). 2016 Apr;95(17):e3379. doi:10.1097/MD.0000000000003379. PubMed PMID: 27124023.
2015 г.
Irena Trbojević Akmačić, Nicholas T Ventham, Evropi Theodoratou, Frano Vučković, Nicholas A Kennedy, Jasminka Krištić, Elaine R Nimmo, Rahul Kalla, Hazel Drummond, Jerko Štambuk, Malcolm G Dunlop, Mislav Novokmet, Yurii Aulchenko, Olga Gornik, IBD-BIOM consortium, Harry Campbell, Maja Pučić-Baković, Jack Satsangi, Gordan Lauc Inflammatory bowel disease associates with pro-inflammatory potential of the IgG glycome. Inflamm Bowel Dis. 2015 Jun;21(6):1237-47. doi: 10.1097/MIB.0000000000000372. [IF=5.5]
Sanchez-Juan P, Bishop MT, Kovacs GG, Calero M, Aulchenko YS, Ladogana A, Boyd A, Lewis V, Ponto C, Calero O, Poleggi A, Carracedo Á, van der Lee SJ, Ströbel T, Rivadeneira F, Hofman A, Haïk S, Combarros O, Berciano J, Uitterlinden AG, Collins SJ, Budka H, Brandel JP, Laplanche JL, Pocchiari M, Zerr I, Knight RS, Will RG, van Duijn CM. A genome wide association study links glutamate receptor pathway to sporadic creutzfeldt-jakob disease risk. PLoS One. 2015 Apr 28;10(4):e0123654. doi: 10.1371/journal.pone.0123654. [IF=3.5]
Tsepilov YA, Shin SY, Soranzo N, Spector TD, Prehn C, Adamski J, Kastenmüller G, Wang-Sattler R, Strauch K, Gieger C, Aulchenko YS, Ried JS. Nonadditive Effects of Genes in Human Metabolomics. Genetics. 2015 Jul;200(3):707-18. doi: 10.1534/genetics.115.175760. Epub 2015 May 14. PubMed PMID: 25977471; PubMed Central PMCID: PMC4512538. [IF=6.0]
Xia Shen, Xiao Wang, Zheng Ning, Yakov Tsepilov, Masoud Shirali, Blair H. Smith, Lynne J. Hocking,Sandosh Padmanabhan, Caroline Hayward, David J. Porteous, Yudi Pawitan, Chris S. Haley, Yurii S.Aulchenko, Generation Scotland, Simple multi-trait analysis identifies novel loci associated with growth and obesity measures. bioRxiv, July 2015, doi: http://dx.doi.org/10.1101/022269
2014 г.
Versmissen J, Oosterveer DM, Yazdanpanah M, Dehghan A, Hólm H, Erdman J, Aulchenko YS, Thorleifsson G, Schunkert H, Huijgen R, Vongpromek R, Uitterlinden AG, Defesche JC, van Duijn CM, Mulder M, Dadd T, Karlsson HD, Ordovas J, Kindt I, Jarman A, Hofman A, van Vark-van der Zee L, Blommesteijn-Touw AC, Kwekkeboom J, Liem AH, van der Ouderaa FJ, Calandra S, Bertolini S, Averna M, Langslet G, Ose L, Ros E, Almagro F, de Leeuw PW, Civeira F, Masana L, Pintó X, Simoons ML, Schinkel AF, Green MR, Zwinderman AH, Johnson KJ, Schaefer A, Neil A, Witteman JC, Humphries SE, Kastelein JJ, Sijbrands EJ. Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach. Eur J Hum Genet. doi: 10.1038/ejhg.2014.101. [IF=4.23]
Fabregat-Traver D, Sharapov SZ, Hayward C et al. High-Performance Mixed Models Based Genome-Wide Association Analysis with omicABEL software [v1; http://f1000r.es/40b] F1000Research 2014, 3:200 (doi: 10.12688/f1000research.4867.1)
